Galen eCalcs - Calculator: FRAX WHO Fracture Risk
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About FRAX
FRAX® is a sophisticated risk assessment instrument, developed by the University of Sheffield in association with the World Health Organization. It uses risk factors in addition to DXA measurements for improved fracture risk estimation. It is a useful tool to aid clinical decision making about the use of pharmacologic therapies in patients with low bone mass. The International Osteoporosis Foundation supports the maintenance and development of FRAX®.
Calculator Inputs
Input | Mapping Type | Description | |||
---|---|---|---|---|---|
Ethnicity | Demographics | Patient Ethnicity | Sex | Demographics | Patient Sex |
Age | Demographics | Patient Age | |||
Weight | Vitals | Patient’s Weight | |||
Height | Vitals | Patient’s Height | |||
Previous Fracture | Problems / No Default Mappings | A previous fracture in adult life occurring spontaneously, or a fracture arising from trauma which, in a healthy individual, would not have resulted in a fracture | |||
Parental Hip Fracture | Manual Input | History of hip fracture in the patient’s mother or father | |||
Smoking Status | Problems | Patient’s smoking status | |||
Glucocorticoids | Medications | Patient is currently exposed to oral glucocorticoids or has been exposed to oral glucocorticoids for more than 3 months at a dose of prednisolone of 5mg daily or more (or equivalent doses of other glucocorticoids) | |||
Rheumatoid Arthritis | Problems | Patient has a confirmed diagnosis of rheumatoid arthritis | |||
Secondary Osteoporosis | Problems | Patient has a disorder strongly associated with osteoporosis. These include type 1 (insulin dependent) diabetes, osteoporosis imperfect in adults, untreated long-standing hyperthyroidism or premature menopause (less than 45 years old), chronic malnutrition or malabsorption and chronic liver disease | |||
Alcohol (3+ Per Day) | Problems / No Default Mappings | Patient takes 3 or more units of alcohol daily. A unit of alcohol varies slightly in different counties from 8-10g of alcohol. This is equivalent to a standard glass of beer (285ml), a single measure of spirits (30ml), a medium-sized glass of wine (120ml), or a 1 measure of an aperitif (60ml) | |||
Femoral Neck BMD | Results | Femoral neck bone mineral density in g/cm^2
Ventricular Hypertrophy || Results || Whether the patient has left ventricular hypertrophy |
Calculator Outputs
Output | Mapping Type | Description |
---|---|---|
Major Osteoporotic Fracture | Result | Ten year probability of major osteoporotic fracture |
Hip Fracture | Result | Ten year probability of hip fracture |
T-Score | Result | Bone density at femoral neck when compared to the young normal reference mean |